Evidências para o manejo da cardite reumática: síntese de revisões sistemáticas e desenvolvimento de protocolo assistencial sobre febre reumática

Abstract

Rheumatic fever is a highly prevalent disease, particularly among children, and one of its main complications, chronic rheumatic carditis, significantly impairs quality of life. This condition leads to frequent healthcare visits, financial burdens, disruptions in daily activities, hospitalizations, and, in severe cases, cardiac surgery or death. This study aimed to conduct an umbrella review (systematic review of systematic reviews) on therapeutic interventions for the prevention of chronic rheumatic carditis and its complications, with the purpose of developing a clinical care protocol to support pediatric management. Database searches were performed, followed by study selection and quality assessment, and the extracted data informed the development of the protocol in accordance with current guidelines. The findings indicate that the benefits of available treatments for preventing chronic rheumatic carditis and its complications remain uncertain, highlighting the need for further studies with robust methodologies to determine their effectiveness.