Relação entre estado nutricional, fatores clínicos e hábitos de vida com a abundância de Prevotella spp na microbiota intestinal humana

Abstract

Growing evidence indicates that the gut microbiota plays a fundamental role in metabolic health and that factors such as diet and lifestyle influence its composition. This study investigated the relationship between nutritional status, lifestyle habits, and clinical intestinal variables with the abundance of Prevotella spp. in the human gut microbiota. Data from 125 patients treated at a primary health care clinic in Uberlândia, Minas Gerais, between October 2022 and April 2023 were analyzed. Gut microbiota composition was determined through metagenomic sequencing of fecal DNA. A statistically significant relationship was observed between BMI and Prevotella bivia (p = 0.033), suggesting a possible association with eutrophic status. The other analyzed variables showed no significant associations with Prevotella species. It is concluded that the abundance of this bacterium in the gut microbiota is influenced by multiple contextual factors, reinforcing the importance of individualized strategies for promoting gut health.