Popriedades ópticas de tecido ósseo e modificações estruturais e mecânicas - Principais achados na literatura.

Abstract

The relevance of bone quality assurance is unquestionable, considering that the various functions of bones, such as skeletal support, ensure body homeostasis and the proper functioning of the human body. Studies related to the diagnosis and treatment of bone diseases contribute to improvements in public health. The techniques of Raman spectroscopy and Fourier Transform Infrared Spectroscopy (FTIR) act in a complementary way in the characterization of bone tissue. Thus, there has been some promise in this application. It was found from the survey of selected articles from the literature that the interesting wavelength range is 400-1750 cm-1 for Raman spectroscopy, in wich allows the visualization of the main mineral and matrix bands of the bone and the range of 400-3600 cm-1 for FTIR spectroscopy wich can be used to the identified the bands assigned to the functional groups relative to water and hydroxyapatite. Based on the analysis of the articles, there was a progress in obtaining information about of the main functional groups indicative of change in bone tissue due to the onset of diseases. It was also noted a technological improvement with regard to the experimental apparatus, in addition to the possibility of applying Raman imaging in vivo.