Análise da utilidade da ultrassonografia na quantificação da gordura visceral, gordura perirrenal e gordura subcutânea em portadores de síndrome metabólica e associação com fatores de risco cardiovascular

Abstract

Background: The metabolic syndrome (MS) brings together a number of pro- atherogenic and pro-thrombotic risk-factors, which often culminate in premature death caused by atherosclerotic cardiovascular disease and ischemic events. Objectives: To evaluate the usefulness of ultrasonography (US) in the quantification of abdominal subcutaneous (SCF), visceral (VF) and peri-renal (PRF) fat deposits in healthy volunteers and in patients with MS, correlating the measurements obtained with the variables linked to increased risk of ischemic cardiovascular events. Methods: A cross-sectional study was carried out, initially with 101 volunteers, to validate the ultrasound measurement method. Correlation analyzes were performed using visceral, perinenal and subcutaneous fat measurements with the various variables linked to the clinical diagnosis of the metabolic syndrome. Results: The values of VF showed significant positive correlations with glucose (GLC), waist circumference (WC), triglycerides (TG), glutamic oxaloacetic transaminase (GPT), systolic blood pressure (SBP), diastolic blood pressure (DBP), and a positive borderline correlation with gamma- glutamyl-transferase (γGT). The values of PRF showed significant positive correlations with WC, TG, HDL-C, LDL-C, total cholesterol (TC), GPT, SBP and DBP.. The values of PRF showed positive correlations with GLC, WC, TG, GPT, SBP and DBP, and a positive borderline correlation with γGT. Conclusion: The abdominal US is a valid and reproducible method in the evaluation of VF, PRF andSCF, which have positive correlations with the main variables linked to MS.