Salmonella Heidelberg isoladas de alimentos e pacientes humanos: Susceptibilidade aos antimicrobianos

Abstract

Bacteria of the genus Salmonella are often related to outbreaks of human infections worldwide, being transmitted by the consumption of contaminated foods, mainly those of animal origin, especially the meat of chicken. Among the microorganisms belonging to the genus Salmonella, serovar Heidelberg is considered to be invasive and capable of causing diseases of greater severity to humans and is frequently resistant to antimicrobials. This reinforces the concern with this serovar, as the emergence of antimicrobial resistant strains of salmonella has become a growing concern for food safety, and consequently for public health. The objective of this study was to evaluate the susceptibility of S. Heidelberg isolates to antimicrobials belonging to the most important classes for human and veterinary use: ceftriaxone, colistin and meropenen. The minimum inhibitory concentration (MIC) test was used to evaluate 14 strains of Salmonella Heidelberg, three isolates of clinical material from humans and 11 isolates from food during the years 2011 to 2017. The samples had a resistance profile of 21,4% for ceftriaxone and 14.29% for colistin, whereas for meropen 100% of the strains were sensitive to the antibiotics tested. The results confirmed an increase in antimicrobial resistance tested in Salmonella Heidelberg isolated from human patients and in animal production, which warns of a potential risk to public health, requiring constant monitoring in animal production, as well as the rational use of antimicrobials, as a way of avoiding failures in the treatment of salmonellosis, and consequently, persistent infections in both animals and humans.