Análise crítica do uso de antimicrobianos tópicos e sistêmicos em pacientes queimados internados no Hospital de Clínicas de Uberlândia

Abstract

Burns are among the leading causes of morbidity and mortality in developing countries and is the ideal environment for infection accounting for at least 75% of death cases. Mortality is bimodal with an early peak associated with the shock of burnt and / or inhalation injuries and a peak linked to septic complications. During the 15 year period 2000-2015 two hundred twenty-three (68%) were classified as having severe burns, satisfying the criteria and were included in our study. The smoking was present increasing the chance of infection in 5.37 times, Alcoholism was not significant when related to infection in burn. The risk of infection in patients was 4.4 times higher among those hospitalized longer than 15 days. Patients suffering from sunburn on the street have the 3.7 times greater risk of infection than patients suffering burns in other environments. The infection was present in 90 cases (39.1%) with positive culture infection in burn site (17.4%), urine (6.5%), lung (6.1%) bloodstream infections (5, 2%), catheter infection (3.25%). The agents were Staphylococcus aureu (4.3%), Pseudomonas sp. (3.9%) Escherichia coli (3.5%) Acinetobacter baumannii (3.0%).