Análise da osseointegração de implantes instalados em áreas enxertadas com diferentes biomateriais xenógenos: um estudo pré-clínico em ratos

Abstract

This study evaluated the osseointegration of implants placed in areas grafted with two different xenogeneic biomaterials. Thirty-two rats were randomly assigned to two groups (n = 16) according to the biomaterial used: Cerabone – implants placed in areas grafted with Cerabone (Botiss, Zossen, Germany); Bio-Oss – implants placed in areas grafted with Bio-Oss (Geistlich Biomaterials, Wolhusen, Switzerland). Grafting procedures were performed in the tibiae, and after 60 days, the implants were placed. Animals were euthanized at 15 and 45 days after implant placement. Biopsies containing the implants were fixed. Histomorphometric analysis was performed to assess bone-to-implant contact (%BIC) and the percentage of bone volume between the implant threads (%BBT). Histomorphometric analysis revealed no statistically significant differences in %BIC or %BBT between the Cerabone and Bio-Oss groups at either evaluation period. The type of xenogeneic biomaterial used for grafting did not affect the osseointegration of implants in this experimental model.