O uso da sacarose para analgesia em neonatos durante procedimentos dolorosos: uma revisão de escopo

Abstract

The sensation of pain in newborns can cause negative effects on them, due to the immaturity of their nervous system, they are more sensitive to painful stimuli. In this context, the administration of sucrose, a non-pharmacological method, is carried out due to its analgesic effects in newborns and premature babies. This work aims to map evidence in the literature that answers the question “How to administer sucrose for analgesia in neonates during painful procedures?”. A literature search was conducted in May 2024 in the MedLine (via PubMed), LILACS/CUMED, SciELO, EMBASE, Scopus and Web of Science and LIVIVO databases. This review included randomized clinical trials, carried out between the years 2014-2024, in infants up to six months of age. We performed a double-blind selection and data extraction was the responsibility of a reviewer. The results were described in a narrative and descriptive manner. The electronic search located 6588 articles, of which 86 were included in the review. As a result, it was possible to observe a variety of methods of administration of sweet solutions, however, a prevalence in the use of sucrose of 24%, with a volume of 2 mL, administered 2 minutes before the procedure, with pain assessment through the PIPP scale. Therefore, it is concluded that there is a need to develop a protocol standardizing the use of sweet solutions.