Vacinação de Pré-exposição contra a Raiva Humana em Profissionais do Hospital Universitário Veterinário do Triangulo Mineiro: Titulação Sorológica pós-Vacinação

Abstract

The objective of the study was to evaluate the serological risk of pre-exposure vaccination against rabies in professionals at the UFU Veterinary Hospital. With a quantitative approach, it analyzed 30 participants, 21 females and 9 males vaccinated with three intradermal doses. The results indicated a drop in antibody levels between 2016 and 2018, with the average number of antibodies intramuscularly being 2.15 IU/ml, with values varying between 0.18 IU/ml and >5.34 IU/ml; and intradermally there are changes in titer rates, in 2016, the average was 4.18 IU/ml, with 76.9% for females and 100% for males presenting titers above 5.34 IU/ml and in 2018, this average was reduced to 1.87 IU/ml, and there was no proportion of titers above 5.34 IU/ml. It is concluded that the data analyzed expresses a worrying reduction in antibody levels over time in the study population. I emphasize that carrying out post-vaccination serological assessments and the application of regular boosters are essential strategies to guarantee adequate levels of occupational protection and safety.