Mulheres com fadiga relacionada à quimioterapia, apresentam fraqueza muscular

Abstract

Breast cancer is a complex and heterogeneous disease, with several molecular subtypes that require specific therapies. Late diagnosis in Brazil, in advanced stages, contributes to a high mortality rate, being the main cause of death from cancer in women. Treatment involves local (surgery, radiotherapy) and systemic (chemotherapy, hormone therapy) approaches, but can result in significant side effects, such as cancer-related fatigue (CRF). A systematic review of randomized clinical trials is proposed to investigate the effects of chemotherapy on peripheral muscle strength in women with breast cancer. This research seeks to better understand the impacts of treatment on quality of life, considering the persistence of CRF even after the end of treatment. The study aims to contribute to strategies for managing the secondary effects of treatment and improving patients' quality of life.