Análise e aplicação da ferramenta de bioinformática geo cancer prognostic dataset retriever em dados genômicos gene expression omnibus (GEO) para prognósticos de câncer

Abstract

Cancer is present in the daily lives of many people, directly affecting their lifestyles, which requires the production of data and research in the oncological area. This work can be used as supporting material providing necessary or accessory information for data processing and the application of a bioinformatics tool impacting oncology research. The objective of the work was to describe the application of the geoCancerPrognosticDatasetsRetriever bioinformatics tool freely available in the Perl programming language to identify cancer prognostic datasets provided by the public genomic data repository Gene Expression Omnibus (GEO). In the analyzed tool, different commands can be used for different cancer prognoses, with the aim of optimizing the search in the repository. The tool's function is to group cancer prognosis data and quickly provide all datasets published in the repository. Therefore, the time spent using the tool is significantly less when compared to manual grouping directly on the GEO repository website. This way we can easily use the prognostic gene expression data grouped by the tool and provided by the repository, offering greater usability for the researcher, who is not always an expert in bioinformatics.