Processo de ajuste de medicamentos sólidos orais para administração via sonda enteral em um hospital universitário de uberlândia

Abstract

Eventually, oral administration of medications is not possible or not advisable, and in these cases, the use of alternative routes of administration may be quite convenient. However, problems related to tube obstruction, incompatibilities between drugs and enteral diet, increased adverse effects, and reduced efficacy and safety of drugs may occur. These problems can be minimized with the correct orientation of the clinical pharmacist about the correct selection of the drug, pharmaceutical form, route of administration, drug interactions and incompatibilities with enteral nutrition. Thus, the objective of this study was to conduct a literature review, identifying the main recommendations to be adopted on the preparation and administration of medications in hospitalized patients using enteral tubes, in order to guide the development of an orientation manual for the adjustment of oral medications standardized in the institution for administration through enteral tubes. The literature review was carried out in SciELO, PubMed/Medline Lilacs and Cochrane Library, in English, Portuguese and Spanish, with publication years between 2000 and 2022. Then, to prepare the manual, a literature review was performed and a search was made in the following databases: Micromedex, Handbook of Drug Administration via Enteral Feeding Tubes, Uptodate, Lexicomp online, Dynamed, as well as the websites Drugs.com and Bulário Eletrônico, in the model already standardized by EBSERH, which will be presented as a residency conclusion work. It is expected that the manual will help the multidisciplinary team in the choice of the appropriate pharmaceutical form for administration via enteral tube, contributing to the process of care and patient safety.