1. Repositório Institucional - Universidade Federal de Uberlândia
  2. Faculdade de Odontologia (FOUFU)
  3. TCC - Odontologia
Please use this identifier to cite or link to this item: https://repositorio.ufu.br/handle/123456789/36700
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dc.creatorFreitas, Gabrielle Alves Nunes-
dc.date.accessioned2023-01-10T17:33:44Z-
dc.date.available2023-01-10T17:33:44Z-
dc.date.issued2022-12-05-
dc.identifier.citationFREITAS, Gabrielle Alves Nunes. Efeitos de diferentes materiais à base de silicato de cálcio na resistência à fratura de dentes permanentes imaturos com reabsorção radicular por substituição e na osteoclatogênese: um estudo laboratorial. 2022. 26 f. Trabalho de Conclusão de Curso (Graduação em Odontologia) – Universidade Federal de Uberlândia, Uberlândia, 2023.pt_BR
dc.identifier.urihttps://repositorio.ufu.br/handle/123456789/36700-
dc.languageengpt_BR
dc.publisherUniversidade Federal de Uberlândiapt_BR
dc.rightsAcesso Embargadopt_BR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectFracture strengthpt_BR
dc.subjectNon-vital toothpt_BR
dc.subjectOsteoclastogenesispt_BR
dc.subjectRoot resorptionpt_BR
dc.subjectSilicate cementpt_BR
dc.titleEfeitos de diferentes materiais à base de silicato de cálcio na resistência à fratura de dentes permanentes imaturos com reabsorção radicular por substituição e na osteoclatogênese: um estudo laboratorialpt_BR
dc.typeTrabalho de Conclusão de Cursopt_BR
dc.contributor.advisor-co1Souza, Gabriela Leite de-
dc.contributor.advisor-co1Latteshttp://lattes.cnpq.br/9883064253002325pt_BR
dc.contributor.advisor1Moura, Camilla Christian Gomes-
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/8078512804636882pt_BR
dc.contributor.referee1Soares, Priscilla Barbosa Ferreira-
dc.contributor.referee1Latteshttp://lattes.cnpq.br/5032809676969673pt_BR
dc.contributor.referee2Soares, Carlos José-
dc.contributor.referee2Latteshttp://lattes.cnpq.br/3485765805045929pt_BR
dc.contributor.referee3Peres, Thiago Silva-
dc.contributor.referee3Latteshttp://lattes.cnpq.br/2751102862279585pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/5068277507006722pt_BR
dc.description.degreenameTrabalho de Conclusão de Curso (Graduação)pt_BR
dc.description.resumoObjective(s): This study evaluated the effects of Biodentine (BD), Bio-C repair (BCR), and mineral trioxide aggregate plug (MTA) on fracture resistance of simulated immature teeth with replacement root resorption (RRR) and in vitro induced osteoclastogenesis. Materials and Methods: Sixty bovine incisors simulating immature teeth and RRR were divided into five groups: BD and BCR, completely filled with respective materials; MTA, a 3-mm apical plug of MTA; RRR, no root canal filling (negative control); PL, no RRR, and root canal filling performed (positive control). All the teeth underwent mechanical fatigue, and then compression strength testing was performed using an Instron universal testing machine. RAW 264.7 macrophages were treated with 1:16 extracts of BD, BCR, and MTA containing receptor activator of nuclear factor-kappa B ligand (RANKL) for 5 days. RANKL-induced osteoclast differentiation was assessed by staining with tartrate-resistant acid phosphatase. Fracture load and osteoclast number were analyzed using one-way analysis of variance (ANOVA) and Tukey’s test (α=0.05). Results: No significant difference in fracture resistance was observed among the groups (P>0.05). All materials similarly inhibited osteoclastogenesis (P>0.05), except for BCR, which showed a lower percentage of osteoclasts than MTA (P<0.0001). The presence of RRR did not affect the fracture strength of the simulated immature teeth and the materials tested did not significantly strengthen them. Conclusion(s): The treatment options used to treat non-vital immature teeth with RRR do not strengthen them and provide similar resistance to fractures. BD, MTA, and BCR showed inhibitory effects on osteoclast differentiation, with BCR group showing better results.pt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.courseOdontologiapt_BR
dc.sizeorduration26pt_BR
dc.subject.cnpqCNPQ::CIENCIAS DA SAUDEpt_BR
dc.embargo.termsSerá publicado posteriormente em revista.pt_BR
dc.orcid.putcode126255595-
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