Associação de obesidade sarcopênica com mortalidade em pacientes com doença renal crônica em hemodiálise

Abstract

Introduction: Obesity, decreased muscle mass and strength are risk factors for mortality in hemodialysis patients. These conditions can occur simultaneously, characterizing sarcopenic obesity and also be associated with mortality in this population. Therefore, the objective is to assess whether sarcopenic obesity is associated with all-cause mortality in patients undergoing hemodialysis. Methods: This is a retrospective observational cohort study that included patients on hemodialysis from January 2013 to July 2017. Patients were followed up until July 2019. For sarcopenic obesity diagnosis, a combination of the diagnosis of sarcopenia (according to the European Working Group of Sarcopenia on Older People consensus) and diagnosis of obesity (according to the percentage of fat according to World Health Organization cutoff points) was used. Kaplan-Meier curves were used to determine the likelihood of survival during follow-up. Results: 98 patients were included, with a mean age of 57.0 ± 14.9 years and follow-up time of 28 ± 16 months. During this period, 27.6% of patients died, 22.4% underwent kidney transplantation, 5.1% were transferred to another dialysis service and 2% changed the dialysis method. Using cutoff points to classify sarcopenic obesity. Sarcopenic obesity prevalence was 7.14% (n = 7) . In the survival analysis, no difference was found between the group with and without sarcopenic obesity (p = 0.401). Conclusion: Sarcopenic obesity was not associated with mortality in hemodialysis patients.