SIAL: automatização de análises de parâmetros espaço-temporais para modelos de comportamento animal no labirinto em cruz elevado e campo aberto

Abstract

Anxiety and depression are diseases of great prevalence upon the population, it is estimated that nearly 9,3 percent of the brazilian population suffers from any kind of anxiety disorder (WHO,2017). Because of this, the study of this disorders becomes significant in the field of general public health of the country. In this sense, many studies are carried out through rodents behavioral models, in order to understand these pathologies. Currently, appliances are used to bring those behaviors in animals that resemble to the symptoms of anxiety and depression, for association, and, analysis methodologies are used in order to quantify such behaviors. The present study aimed to show a new technology created to automate the analysis (SIAL) made currently and only for trained experimenters or by the purchase of another software considered reference in the area. The software SIAL showed itself stable in all the tests, not presenting any statistical difference when compared with the methodology of a trained experimenter and/or the methodology of the reference software, although the need for alterations in the analyzes was observed, since the software still in development needs aditional tests and adjustments to suit a range of other situations.