Associação de aspectos clínicos de cães com cinomose com lesões anatomopatológicas do sistema nervoso central

Abstract

Canine distemper is an infectious illness spread worldwide. The disease’s clinical signs are mostly systemic and there might be neurological manifestation. The present study aimed to report clinical and anatomopathological aspects of the central nervous system of dogs diagnosed with canine distemper. It was collected data from 20 animals forwarded to Animal Pathology Laboratory – HV-UFU. The animals were subjected to necropsy and it was collected 18 pre-established fragments of the central nervous system for microscopic analysis. From the studied dogs, 60% were female, 80% were mixed-breed dogs and 80% were adults, with median age of 5 years old. The most observed clinical signs were affections in the locomotion system (55%), where ataxia was the most common one (54,5%); and behavioral change (40%), where 75% of these animals showed apathy. The most important macroscopic finding was leptomeningeal hyperemia. In the microscopy all regions were affected, mainly in the telenchephalic lobes (27%). The most observed lesions were perivascular cuffing, demyelination, gliosis/satelitosis. Association between neurological clinical sign and local of the lesion.