Tratamento multiprofissional do adolescente obeso: efeito nos marcadores da inflamação e do estresse oxidativo

Abstract

The population with obesity has grown in Brazil in the last few decades, including adolescents. Among the most successful strategies for its treatment is multidisciplinary intervention. Thus, the objective of this thesis was to try and understand the effects of multidisciplinary treatment on markers of inflammation and oxidative stress in obese adolescents. Were selected obese adolescents to participate in a multidisciplinary treatment which was attended by doctors, nutritionists, physiotherapists, psychologists and physical educators. The program has a duration of 10 months and were evaluated, in addition to anthropometric parameters and physical performance, the markers of inflammation and oxidative stress. Were produced, with the data collection, two studies. The first a longitudinal study, where were observed improvements in inflammatory parameters and reduction of oxidative stress with the multidisciplinary treatment, in addition to a reduction in the anthropometric parameters related to obesity. The second, a cross-sectional study has identified the association between inflammatory state and cardiorespiratory fitness in obese adolescents, indicating that a good cardiorespiratory capacity reduces, regardless of the level of obesity, the consequences caused by chronic inflammation. These two studies can be read in detail in the chapters of this thesis. In general, we conclude that the multiprofessional treatment is able to promote positive changes in markers of inflammation and oxidative stress in obese adolescents.