Análise do efeito da sulfadiazina de prata e do confrei na cicatrização cutânea de ratos wistar

Abstract

The skin covers the entire body, because it is the largest organ of the body is composed of three distinct layers, it is extremely important physiological. The present study was conducted surgical incisions in rats and tested the effectiveness of two drugs, comfrey and silver sulfadiazine in tissue repair analyzing extracellular matrix, level of re-epithelialization of skin collagen quantification, counting of mast cells,Count of blood vessels, Determination of hemoglobin Dosage ,Dosage of NAG activity, and activity myeloperoxidase. Soon this work aims and main scope is to provide a more thorough analysis and scientific content of Symphytum officinale (comfrey) widely used in popular culture for its healing properties anti-inflammatory and healing in dermatological treatment comparing well with agent widely used silver sulfadiazine 1%. Concludes that the comfrey plays a key role in wound healing with its anti-inflammatory and certainly opens up new possibilities for action, based on the mechanism of degranulation of mast cells and neutrophils during the repair phase, decreased angiogenesis best arrangement of collagen and has the potential to provide better performance for the healing of wounds.