Avaliação dos componentes hematológicos, perfil protéico sérico e concentração da IgA salivar e sérica, em cães com gastroenterite canina

Abstract

Saliva is an oral fluid abundant with molecules, being non-invasive, easy collection and with minimal discomfort to the animal, with great potential for the overall monitoring of health and disease, with huge prognostic values. The Immunoglobulin A is the first in line of immunological attack of mucosal tissue. The Canine Gastroenteritis is the most common case series in medical veterinary clinic originating through various sources, as the viral the most common. The main objective of the present study is the quantification of IgA in the saliva of dogs affected by gastroenteritis and to compare the results with the amounts found in healthy dogs as well as quantifies the hematologic and serum biochemistry, confirming if they represent standards of differential diagnosis for the disease here investigated. The GEV group presented eosinopenia, neutropenia, monocytopenia, serum hypoproteinemia, hypoalbuminemia serum and salivary hyperproteinemia. The serum IgA showed a decrease when comparing with the control group. For group GEG presented eosinopenia, neutrophilia with left shift. Also showed microcytosis, hypoproteinemia, hypoalbuminemia and salivary hyperproteinemia but with no statistical difference for these parameters. We conclude that the measurements of total leukocytes along with the segmented neutrophils, eosinophils, dosage and serum albumin PT and also the determination of PT showed increased salivary IgA and quantification decreased, suggesting parameters for diagnosing disease. However, because the definition of reference value missing, most studies dosing canine IgA should be performed.