1. Repositório Institucional - Universidade Federal de Uberlândia
  2. Faculdade de Medicina (FAMED)
  3. TCC - Enfermagem
Por favor, use este identificador para citar o enlazar este ítem: https://repositorio.ufu.br/handle/123456789/48154
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Campo DCValorLengua/Idioma
dc.creatorNatal, Ana Catarina de Castro-
dc.creatorMenezes, Ralciane de Paula-
dc.creatorRöder, Denise Von Dolinger de Brito-
dc.date.accessioned2026-02-04T12:12:01Z-
dc.date.available2026-02-04T12:12:01Z-
dc.date.issued2024-12-11-
dc.identifier.citationNATAL, Ana Catarina de Castro; MENEZES, Ralciane de Paula; RÖDER, Denise Von Dolinger de Brito. Role of maternal milk in providing a healthy intestinal microbiome for the preterm neonate. Pediatric Research, v. 97, n. 6, p. 2235–2242, 2025. DOI https://doi.org/10.1038/s41390-024-03751-xpt_BR
dc.identifier.urihttps://repositorio.ufu.br/handle/123456789/48154-
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Uberlândiapt_BR
dc.rightsAcesso Abertopt_BR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectPreterm neonatept_BR
dc.subjectMaternal milkpt_BR
dc.subjectGut microbiomept_BR
dc.subjectInfectionspt_BR
dc.titleRole of maternal milk in providing a healthy intestinal microbiome for the preterm neonatept_BR
dc.typeTrabalho de Conclusão de Cursopt_BR
dc.contributor.advisor-co1Menezes, Ralciane de Paula-
dc.contributor.advisor-co1Latteshttp://lattes.cnpq.br/9034808411886042pt_BR
dc.contributor.advisor1Röder, Denise Von Dolinger de Brito-
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/5521478892510854pt_BR
dc.contributor.referee1Leal, Geraldo Sadoyama-
dc.contributor.referee1Latteshttp://lattes.cnpq.br/5245055964402823pt_BR
dc.contributor.referee2Ferreira, Isadora Caixeta da Silveira-
dc.contributor.referee2Latteshttp://lattes.cnpq.br/9029019557273261pt_BR
dc.description.degreenameTrabalho de Conclusão de Curso (Graduação)pt_BR
dc.description.resumoThe immature gastrointestinal tract of preterm neonates leads to a delayed and distinctive establishment of the gut microbiome, making them susceptible to potentially pathogenic bacteria and increasing the risk of infections. Maternal milk, recognized as the optimal source of nutrition, plays a multifaceted role in modulating the gut microbiome of premature newborns. Human milk oligosaccharides, acting as prebiotics, provide essential nourishment for key bacteria such as Bifidobacterium, contributing to the proliferation of beneficial bacterial populations. Additionally, maternal milk is rich in Immunoglobulins that stimulate immune cell responses, providing protective effects on the infant’s gut mucosa. Moreover, bioactive proteins such as secretory immunoglobulin A (SIgA), lactoferrin, lysozyme, and mucins play a crucial role in defending against pathogens and regulating the immune system at the cellular level. These proteins contribute not only to infection prevention but also emphasize the impact of breast milk in fortifying the body’s innate defenses. This multifaceted role of maternal milk, including essential nutrients, beneficial bacteria, and bioactive proteins, highlights the importance of promoting the mother’s own milk feeding in the Neonatal Intensive Care Unit (NICU). It not only optimizes the long-term outcomes and well-being of preterm infants but also provides a holistic approach to their health and development.pt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.courseEnfermagempt_BR
dc.sizeorduration8pt_BR
dc.subject.cnpqCNPQ::CIENCIAS DA SAUDEpt_BR
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