Carcinoma secretório de glândulas salivares do lábio superior em adolescente: relato de caso

Abstract

Secretory carcinoma (SCSG) is a low aggressive malignant neoplasm of the salivary glands. Its existence was only recognized in 2010, with few cases described in the literature. It primarily results from chromosomal translocations that alter the ETV6 gene. It presents characteristic microscopic morphological and immunohistochemical features similar to breast carcinomas. This carcinoma has been described in a wide age range. Most cases are identified in major salivary glands, and its occurrence on the lip is particularly uncommon. The present study reports the case of a 14-year-old male patient, attended for evaluation of a nodule on the upper lip. After incisional biopsy, histopathological and immunohistochemical examination established the diagnosis of SGSC. The lesion was surgically removed and there is no evidence of recurrence 30 months after treatment.