Hipercortisolismo em cães: atualização da classificação e opções terapêuticas

Abstract

Hypercortisolism it’s an endocrinopathy frequently diagnosed in dogs. This condition refers to the increase in glucocorticoid activity, which generates clinical signs such as polyuria, polydipsia, polyphagia, abdominal bulging, and sarcopenia, in addition to other symptoms. Hypercortisolism can have a pituitary or adrenal source, and this distinction must be sought, since the treatment options become increasingly wide, making it possible to associate recent therapeutic discoveries and research, with the known and most used forms of treatment. Previously, hypercortisolism was referred to as a synonym of “hyperadrenocorticism” or “Cushing's Syndrome”, however, it’s currently possible to differentiate those concepts so that they are used correctly, and from that, the diseases can be better defined and diagnosed then treated. From this, the present work is a literature review that had as its objective to update terminologies, diagnostic standards, and treatment options for canine hypercortisolism.