Please use this identifier to cite or link to this item: https://repositorio.ufu.br/handle/123456789/33130
ORCID:  http://orcid.org/0000-0002-2844-3474
Document type: Trabalho de Conclusão de Curso
Access type: Acesso Embargado
Title: Coordination compounds against multi-drug resistant bacteria: a critical review
Author: Benedicto, Christian Cavalini
Neto, Antônio Marçal
Menezes, Ralciane de Paula
Jardim, Ana Carolina Gomes
Abbehausen, Camilla
Bergamini, Fernando Rodrigues Goulart
Martins, Carlos Henrique Gomes
First Advisor: Martins, Carlos Henrique Gomes
First coorientator: Bergamini, Fernando Rodrigues Goulart
First member of the Committee: Pedroso, Reginaldo dos Santos
Second member of the Committee: Paiva, Raphael Enoque Ferraz de
Summary: In the effort to shed some light on the bacterial multiresistance problem and the lack of a dynamic approach able to overcome the drug innovation gap, coordination compounds arise as a very promissing source of potential antibacterials. Ubiquitously active against several biomolecular components of the bacterial cell, these potential therapeutics have presented low probability of resistance development . As adjuvants those compounds were shown to reverse bacterial resistance against certain antibacterial drug. Herein the readership will find both historically revelant and current developments of coordination compounds encompassing transition and post-transition metal complexes as well as metalloid-based molecules that have shown activity against resistant strains. Seeking to further stimulate drug development, pivotal information regarding virulence and resistance factors of nosocomial pathogenic bacteria can also be found as bullet statements.
Keywords: Compostos de coordenação
Coordination compounds
Bactérias
Bacteria
Resistência a múltiplos fármacos
Multi-drug resistance
Area (s) of CNPq: CNPQ::CIENCIAS BIOLOGICAS::MICROBIOLOGIA
CNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICA::QUIMICA INORGANICA
Language: por
Country: Brasil
Publisher: Universidade Federal de Uberlândia
Quote: BENEDICTO, Christian Cavalini; NETO, Antônio Marçal; MENEZES, Ralciane de Paula; JARDIM, Ana Carolina Gomes; ABBEHAUSEN, Camilla; BERGAMINI, Fernando Rodrigues Goulart; MARTINS, Carlos Henrique Gomes. Coordination compounds against multi-drug resistant bacteria: a critical review. 2021. 17 f. Trabalho de Conclusão de Curso (Graduação em Biomedicina) - Universidade Federal de Uberlândia, Uberlândia, 2021.
URI: https://repositorio.ufu.br/handle/123456789/33130
Date of defense: 28-Sep-2021
Appears in Collections:TCC - Ciências Biomédicas

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