Efeito da laserterapia de baixa intensidade com duplo comprimento de onda e da fibrina rica em plaquetas sobre o reparo de sítios pós extração de terceiros molares: Estudo clínico, controlado e randomizado em modelos de boca dividida

Abstract

This project aimed to evaluate the effect of fibrin-rich plasma membranes (FRP) and low-intensity dual-wavelength laser therapy on alveolar repair in post-extraction sites of third molars. For this, 20 patients were involved in this study who underwent extraction of 4 third molars, which were treated as follows in a split-mouth model: Upper molars: Test side was treated filled with PRF membrane while the control side was kept with blood clot. Mandibular molars: Test side was treated for low-intensity dual wavelength laser irradiation (660 nm red laser and 808 nm infrared laser) while the control side was not irradiated. The selection of sides that received the treatments will occur randomly. LLLT was applied immediately and 3 and 7 days after the surgical procedure. The healing of the alveolar process was analyzed by means of a bone healing score, bone density and fractal analysis in the periods of 1 week and 90 days after the surgical procedure by means of CT scans. Additionally, clinical analyzes were performed in the periods of 3, 7, 14, 30 and 90 days after the surgical procedure to assess the occurrence of pain, edema and bleeding, as well as the quality of soft tissue healing, which were assessed using a visual scale analog. It was found that the application of LLLT reduced edema and improved soft tissue healing up to 7 days after surgery. Regarding the use of PRF, there were no clinical differences regarding treatments in any experimental period. Within 7 days, the alveoli treated with PRF had higher bone density than the control alveoli. It can be concluded that dual-wavelength LLLT improved the postoperative clinical course in patients undergoing lower third molar extraction, without altering bone healing. On the other hand, the use of L-PRF does not add clinical advantage in the healing of alveoli after maxillary third molar extraction.