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Antidepressants determination using an electroanalytical approach: A review of methods

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Some substances act in the nervous system central, which are used in the treatment in the depression diseases by control of the reactions to minimizing the disturbances generated, and they are classified as antidepressants. This class have been most used in all world, due to genetic factors, environmental problems, modern lifestyle. Nonetheless, the ingestion of inadequate concentrations can provoke adverse effects for the patient, because the antidepressants have toxicity concentrations. Therefore, each country has safety policies to control these compounds in different samples. In this review shows the classification of the antidepressants permitted in Brazil according to the mode of actuation in the nervous system and the description of actuation type them. In reason of the control of the concentration of these substances in the biologic sample, water, and pharmaceutical formulations was realized a brief bibliographic survey of the electrochemical techniques that can be employed to the determination of antidepressants. Thus, it was described in detail about the electrochemical techniques and electrodes used in the antidepressants determination and alterations to improve analytical parameters and follow the guidelines of Green Analytical Chemical.

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Antidepressants, Electroanalytical techniques, Pharmaceuticals compounds, Carbon-based electrode, Chemical modified electrode

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PIMENTA, Laura Camargos. Antidepressants determination using an electroanalytical approach: a review of methods. 2020.46 f.Trabalho de Conclusão de Curso (Graduação em Biotecnologia) – Universidade Federal de Uberlândia, Patos de Minas, 2021.

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