Preditores de mortalidade em pacientes com doença pulmonar avançada em oxigenoterapia domiciliar prolongada

Abstract

Proposal: To determine the predictors of mortality in patients with Advanced Lung Disease (DPA) in Oxygen Therapy Homecare Extended (ODP), assess the main causes of mortality and survival of these patients. Methods: A retrospective cohort study that evaluated the data of 553 patients with DPA in ODP between the period 2009 to 2015. The patients were divided into two groups: Death and died, to analyze the results evaluated. Results: In this way, we find that most of the population studied were women, smokers and elderly, with anthropometric assessment within the normal range, but lower values for body mass index (BMI) and waist-hip ratio (WHR) in death group . Regarding the functional assessment, we found low levels in lung function parameters and exercise capacity, with a significant difference only in forced expiratory volume in one second after bronchodilator. In addition, metabolic assessment was conducted, comorbidities and quality of life which highlighted changes in the values of lymphocytes and total cholesterol among the groups. The patients who used oxygen for a short time every day had higher mortality, and found as the main risk factors associated with mortality of these patients: the variables FEV 1 post BD, depression and smoking cessation. The main cause of death was respiratory system to approximately 50.4% with respect to the place of death was the highest proportion in hospitals compared with the mortality in the household. We also found that less than 30% of patients with Advanced Lung Disease, have five-year survival. Conclusion: Patients with DPA in ODP present as predictors of mortality: tobacco intake and cessation of time, BMI, ICQ, ODP, post BD FEV1 and total cholesterol. The main cause of mortality are the exacerbation of respiratory diseases, have a low survival rate and the highest place of death are hospitals.