Uso do Lufenuron no tratamento de dermatofitose em Puma concolor (Linnaeus, 1771) - relato de caso

Abstract

Dermatophytoses are fungal infections caused by microorganisms of the genus Microsporum, Trichophyton and Epidermophyton, that act on keratinized tissue on the corneal extract of the epidermis. Caracteristic lesions of this enfermity are round, alopecic and desquamative with inflamamed edges that may or may not present pruritus, hyperkeratosis or hypertrophy of the tissue. Patient immunity is considered to be the main factor related to the severity of the disease, therefore immunosuppressed patients, such as puppies, senile animals or with some other active disease are more susceptible to have more serious injuries. Diagnosis is based on clinical history and aspect of the lesions associated to the microscopic exam of the skin and hair and the fungal culture as confirmatory diagnosis of the disease and infectious agent. At the moment, no current treatment has been completely satisfactory, but the most commonly applied are shampoos composed of chlorhexidine, miconazole or enilconazol and systemic doses of griseofulvin. Lufenuron is a recent assortment for treatment hat acts by inhibiting the synthesis of chitin, main componente of the cell wall of the fungus. The following article reports the effective treatment of dermatophytoses caused by the fungus of the genus Microsporum in puma (Puma concolor) free-living using lufenuron.