Combinação da amplitude de distribuição dos glóbulos vermelhos e do índice de massa corporal (COR-IMC) prediz mortalidade intra-hospitalar em pacientes com diferentes diagnósticos?

Abstract

Background: COR-BMI (combination of red blood cell distribution width and body mass index) is indicated as a new prognostic index of survival in patients with laryngeal cancer. However, it is not yet known about the ability of this prediction in other types of cancer or whether its use can be expanded to non-oncological patients. The aim of this study was to investigate the in-hospital mortality prediction of COR-BMI in oncological and non-oncological patients. Method: A retrospective study was performed with all hospitalized patients between 2014 and 2016, totaling 2930 patients, 262 oncological and 2668 non-oncological. COR-BMI was divided into three categories: 0- RDW ≤ 13.1 and BMI ≥ 25; 1- RDW ≤ 13.1 and BMI <18.5 or ≥ 18.5 <25 and RDW > 13.1 and BMI ≥ 18.5 < 25 or BMI ≥ 25; 2- RDW > 13.1 and BMI <18.5. In order to analyze the relationship between COR-BMI and in-hospital mortality in the studied population, the Cox proportional hazards model was used in a multivariate analysis based on a conceptual model. Results: COR-BMI was an independent predictor of in-hospital mortality in non-oncological patients (HR = 2,84; CI: 1,28-6,31). The survival rate of patients was lower with the highest score in COR-BMI. This prediction was not found in oncological patients. Conclusion: the present study suggests that COR-BMI may have its expanded practical use for non-oncological patients being an independent prognostic indicator of in-hospital mortality.