Efeitos da associação da suplementação de isoflavona e do treinamento com exercícios combinados sobre a musculatura do assoalho pélvico em mulheres no período pós menopausal: ensaio clínico randomizado controlado duplo cego

Abstract

Introduction: The climacteric is the period of physiological transition from the reproductive to the non-reproductive phase of the woman in which there is a progressive reduction of the functioning of the ovary. O baixo nível de estrogênio no organismo pode causar impacto no sistema urogenital como alterações no funcionamento da musculatura da região, e ligamentos de sustentação e suspensão do assoalho pélvico, como também do aspecto da parede vaginal, podendo ser considerado fator de risco para disfunções do assoalho pélvico. Some alternatives used to mitigate climacteric symptoms are isoflavone supplementation and physical exercise training. There aren’t studies on the effect of these two measures on the pelvic floor musculature of postmenopausal women. Aim: to verify the effects of the association of isoflavone supplementation with combined exercise training on the pelvic floor muscles (PFM) of postmenopausal women. Methods: Twenty-eight postmenopausal women were divided into two groups: ISO + EXE, of volunteers who were supplemented by 100 mg of isoflavone and performed non-specific combined aerobic and resistance training of PFM and PLA + EXE group of women supplemented by placebo corn starch 100 mg) and who performed the same training as the previous group. Volunteers were evaluated before and after 10 weeks of intervention by a blind evaluator for primary outcome (PFM squeeze pressure measured by manometry) and secondary outcome (PFM strength assessed by dynamometry). The results of the intervention on the variables were evaluated by two-way ANOVA with repeated measures with two-way analysis of variance (2 groups and 2-time points). The level of significance considered was p < 0.05. Results: The outcomes of twenty-two volunteers were evaluated. No interaction between group and time was found for a vaginal manometry variable (F (1,10) = 0,144, p = 0,713). No interaction between group and time was also found for a vaginal dynamometric variable (F (1,10) = 4.51, p = 0.06). Conclusion: The association of isoflavone supplementation with combined non-specific PFM training does not promote changes in PFM strength in postmenopausal women. Keywords: pelvic floor, climacteric, exercise, supplementary feeding