Doença auto-imune de tireóide e urticária crônica idiopática: um estudo caso-controle

Abstract

Several studies found a higher prevalence of Autoimmune Thyroid Disease (AITD) in patients with Chronic Urticaria (CU). This relationship may be due to the possible autoimmune etiology in up to half of the cases of Chronic Idiopathic Urticaria (CIU). However the frequency of AITD ranged from 1.14% to 28.6%. The study began by determining whether there is an association between AITD and CU, in a population seen at the same clinic. We compare the frequency of anti-thyroid antibodies and thyroid dysfunction in 49 patients with CIU (group 1) and 112 controls (Group 2). In order to support the result found, we studied the prevalence of CIU in 60 patients with AITD (group 3), compared with 29 patients who had non-immune thyroid disease (NAITD) (group 4). We did not find a statistical difference for the presence of anti-thyroid antibodies or thyroid dysfunction between groups 1 and 2. The same occurred for the presence of CIU among groups 3 and 4. In our study it was not possible to demonstrate a relationship between AITD and CIU, which means that different populations may present a higher or lower degree of association between these illnesses.