Associação de progressão de regurgitação tricúspide e seus desfechos relacionada ao implante de dispositivos cardíacos eletrônicos implantáveis em pacientes com cardiomiopatia chagásica crônica: um estudo unicêntrico

Abstract

Multiple studies have described an association between implantation of cardiac implantable electronic devices (CIEDs) and progression of tricuspid regurgitation after device implantation. However, no study has examined this association in patients with chronic chagas cardiomyopathy. Therefore, the present study aims to evaluate the association between worsening tricuspid regurgitation and clinical outcomes related to CIED implantation. Specifically, it will assess the association between worsening tricuspid regurgitation and the number of hospitalizations for heart failure and/or death in this patient population. The study method consists of a retrospective cohort of 80 patients with CCC who underwent CIED implantation, with the objective of determining whether CIED implantation is associated with worsening tricuspid regurgitation, identifying possible risk factors, and evaluating clinical outcomes. Patients’ medical records will be reviewed, and participants will be divided into those who developed worsening tricuspid insufficiency within 6 months after cied implantation and those who did not, based on the presence of tricuspid insufficiency on a prior 2d echocardiogram. Sociodemographic, clinical, echocardiographic, and electrocardiographic data were collected from 52 patients through chart review. The mean age was 66.6 ± 9.8 years, with a predominance of males (28/52; 53.8%) and white patients (34/52; 65.4%). Thirty-one patients (59.6%) had hypertension and 21 (40.4%) were smokers. The mean BMI was 24.95 ± 3.2 kg/m², the mean left ventricular ejection fraction was 50.1 ± 6.5%, and the mean TAPSE was 20.6 ± 3.1 mm. The most frequent rhythm on the admission electrocardiogram was complete atrioventricular block. The most commonly implanted device was a dual-chamber pacemaker with the lead positioned septally.