1. Repositório Institucional - Universidade Federal de Uberlândia
  2. Faculdade de Medicina (FAMED)
  3. TCC - Enfermagem
Please use this identifier to cite or link to this item: https://repositorio.ufu.br/handle/123456789/47114
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dc.creatorXavier, Analicy Rodrigues-
dc.date.accessioned2025-09-29T15:39:56Z-
dc.date.available2025-09-29T15:39:56Z-
dc.date.issued2025-08-29-
dc.identifier.citationXAVIER, Analicy. Synergistic effects of probiotics and lifestyle interventions on intestinal microbiota composition and clinical outcomes in obese adults. 2025. 32 f. Trabalho de Conclusão de Curso (Graduação em Enfermagem) - Universidade Federal de Uberlândia, Uberlândia, 2025.pt_BR
dc.identifier.urihttps://repositorio.ufu.br/handle/123456789/47114-
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.languageporpt_BR
dc.publisherUniversidade Federal de Uberlândiapt_BR
dc.rightsAcesso Abertopt_BR
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subjectintestinal microbiotapt_BR
dc.subjectprobioticspt_BR
dc.subjectobesitypt_BR
dc.subjectlifestylept_BR
dc.subjecthabitspt_BR
dc.subjectweight losspt_BR
dc.titleSynergistic effects of probiotics and lifestyle interventions on intestinal microbiota composition and clinical outcomes in obese adultspt_BR
dc.typeTrabalho de Conclusão de Cursopt_BR
dc.contributor.advisor-co1Menezes, Ralciane-
dc.contributor.advisor-co1Latteshttp://lattes.cnpq.br/9034808411886042pt_BR
dc.contributor.advisor1Röder, Denise-
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/5521478892510854pt_BR
dc.contributor.referee1Ferreira, Isadora-
dc.contributor.referee1Latteshttp://lattes.cnpq.br/9029019557273261pt_BR
dc.contributor.referee2Faria, Gabriel-
dc.contributor.referee2Latteshttp://lattes.cnpq.br/9435352407128654pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/0399481222613352pt_BR
dc.description.degreenameTrabalho de Conclusão de Curso (Graduação)pt_BR
dc.description.resumoBackground and objective: Obesity is a growing global epidemic. The compo sition of the intestinal microbiota can be influenced by several factors. Studies highlight the role of intestinal bacteria in the pathophysiology of obesity. So, the objective of this study was to investigate whether the use of probiotics, together with healthy lifestyle habits, contributes to weight reduction in obese individuals by analyzing the intestinal microbiota profile. Methods: A prospective study was carried out with 45 adults with obesity. Participants underwent guidance on healthy lifestyle habits, received a probiotic component containing different microbiological strains and were followed for 60 days. Clinical parameters, body composition, biochemical analysis, and intestinal microbiota assessment were performed before and after treatment. After 60 days, it was observed that the bacterial strains present in the probiotic were present in the patients’ intestinal microbiota. Participants also showed improvements in physical activity, sleep quality, and anxiety management, as well as changes in some eating habits, such as a reduction in the consumption of processed foods and a significant increase in water intake. Results: A reduction in BMI, fasting glucose, insulin, HOMA-IR, LDL cholesterol, and triglycerides was observed, in addition to an increase in HDL cholesterol, improvement in bowel move ment frequency, and stool consistency. Analysis of the intestinal microbiota revealed an increase in microbial diversity and a better balance between the bacterial phyla Firmicutes and Bacteroidetes. Conclusions: The changes related to improving the composition of the intestinal microbiota, dietary habits, increased physical activity, reduced anxiety, and better sleep quality have significantly contributed to weight loss and improvements in physiological parameters in obese individuals.pt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.courseEnfermagempt_BR
dc.sizeorduration32pt_BR
dc.subject.cnpqCNPQ::CIENCIAS DA SAUDE::ENFERMAGEMpt_BR
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