Efeito do diamino fluoreto de Prata nas propriedades da dentina irradiada in vivo

Abstract

Patients undergoing radiotherapy in the head and neck region may have one of the most common adverse effects after treatment, caries related to ionizing radiation, and the management of these lesions is still quite challenging for the dentist. The objective of this work was to evaluate the effect of Silver Diamino Fluoride on the chemical and mechanical properties of human dentin irradiated in vivo. For this, twelve healthy third molars and twelve premolars and molars of post-radiotherapy patients were collected. The teeth were divided into two groups (n=12) being a control group, sound teeth, and the group with irradiated teeth. In both groups, 38% Silver Diamino Fluoride (SDF, SDI Limited, Victoria, Australia) was applied. The dentin analysis took place in two stages, before the application of the SDF and after 1 month. The hemisections were analyzed by Fourier transform infrared spectroscopy (FTIR), Knoop microhardness test (KHN) and Surface roughness test. Data were analyzed using two-way ANOVA (irradiation and SDF application), followed by Tukey's post hoc test. The FTIR revealed differences for the irradiation factor for Carbonate (p=), for the SDF application factor to Amide I band (p=), Carbonate (p=) and all ratios, C:F (P=0.004), M:M (P=0.005) and AmidI:Amide III(P=0.007). For KHN, there was a significant difference in the irradiation factor (p= 0.047) and SDF application (p<0.001) between the groups. Surface roughness also showed statistical difference for the irradiation factor (p<0.001) and application of SDF (p<0.001) between groups. The use of SDF on irradiated dentin causes structural changes in the organic portion, reorganization of more soluble minerals and formation/deposition of minerals. Thus, ultimately increasing the mechanical properties of irradiated dentin and reducing its roughness.