Ácido Hialurônico: uma revisão bibliográfica

Abstract

This brief bibliographic review seeks to contextualize the hyaluronic acid molecule, which is a biopolymer belonging to the glycosaminoglycan family, consisting of disaccharide units of D-glucuronic acid (GlcA) and N-acetyl-D-glucosamine (GlcNAc) joined by a bond β-1,3 glycoside. The linear polymer can be synthesized both in the organism of vertebrates and in the capsule of some bacteria and is rich in applications, since its molecule stands out for its fundamental characteristics, which are biocompatibility, hygroscopicity, viscoelasticity, nonimmunogenicity, its ability to degrade without release toxicities and its wide range of MM. With the growing demand of the aesthetic market, the injectable hyaluronic acid technique has become increasingly desirable, since it is a safe and minimally invasive technique. In addition, its applicability has been expanding in other areas of medicine, such as ophthalmology and traumatology.