Associação da adequação do aporte energético recebido por pacientes críticos sépticos com mortalidade

Abstract

Introduction: The adaptation of nutritional prescription to individual needs is crucial for the favorable evolution of critically ill patients. However, there is a lack of studies that assessed the energy intake adequacy based on indirect calorimetry (IC), the gold standard method for assessing resting energy expenditure (REE), in addition to evaluating specific groups, such as critically ill septic patients. Therefore, this study aims to evaluate the association of energy intake adequacy received by septic critically ill patients with mortality during hospitalization in the Intensive Care Unit (ICU), using energy expenditure assessed by IC. Methods: Prospective observational study that enrolled critically ill septic patients in the ICU. REE was assessed using the IC test, performed within 72 hours after the sepsis diagnosis. Adequacy of energy intake was calculated by the ratio between energy intake received and REE, assessed by IC. An inadequate energy intake was considered when the energy intake/REE <70%. Results: one hundred twenty three patients were evaluated, 68.3% male, mean age 62.6±16.7 years. Of these, 73.2% had energetic inadequacy. The mortality rate during ICU stay was 77.2%. Adjusted logistic regression, considering mortality as the dependent variable, showed that energy intake adequacy <70% was associated with a higher risk of mortality. Conclusion: An association was found between the adequacy of the received energy intake and mortality in critically ill patients with sepsis.