Síntese e caracterização de membranas de celulose regenerada a partir da celulose extraída do bagaço de cana-de-açúcar para produção de cuprofane

Abstract

In previous work regenerated cellulose membranes produced from the cellulose extracted from sugar cane bagasse were prepared from an adaptation of the Cuprammonium method. Although it has been possible to produce the membranes, it showed high levels of Cu (II) ions, fact that can impossible their application in medical field. In this work, the preparation of these membranes was realized through changes in the methodology as the removal of an intermediate stage (alkaline bath) and the increase in time in the acid bath for cellulose regeneration. Two membranes were produced: MBAG (using cellulose extracted from sugar cane bagasse) and MROD (using cellulose from Pinnus pulp supplied by Rhodia). With the changes in methodology, the copper (II) percentage on the membrane of MBAG (0.0236%) showed a decrease of about 15 times for the membranes produced in previous works (0.3634%). The cell viability data obtained by the technique of incorporation of vital dyes showed that the membranes MBAG and MROD have no toxicity to cell cultures studied. These results indicate a positive way in order to reuse the sugar cane bagasse cellulose for production of devices used in medicine as membranes for hemodialysis therapy.