Avaliação da resposta inflamatória a materiais obturadores endodônticos de dente decíduo, por meio de implantes intra-ósseos, em guinea-pig

Abstract

In Pediatric Dentistry there are several materials used for pulp therapy. Therefore, due to the above mentioned diversity, this research aimed to evaluate and compare the biocompatibily of some materials through intra osseous implants indicated for this purpose: pastes Guedes Pinto, Vitapex®, CTZ and CTZ without eugenol, according to the FDI recommendations (1980) and ANSI/ADA (1982). It was used forty guinea-pigs, ten for each material, divided into experimental periods of four and twelve weeks. Two intra-osseous implants were carried out on each animal on the lateral region of the madibular symphysis, lateral to the incisors teeth. The external lateral cup wall served as control for the technique. At the end of the observation periods, the specimens were prepared for evaluation histological. The results showed that the CTZ paste presented severe inflammatory reaction, necrotic tissue, limphocytes, foreign body cells, and bone resorption. The CTZ without eugenol paste decresead the intensity inflammatory reactions, but absent/slight in the period of 4 weeks, started to moderate in 12 weeks. The reactions to Vitapex® and Guedes Pinto pastes were absent/slight presenting a general pattern of replacement by bone tissue newly formed. The results allowed to the conclusion that only the Guedes Pinto and Vitapex® pastes presented compatibility levels in the two periods analysed according to the criteria adopted and CTZ and CTZ without eugenol showed the lack of biocompatibility.