Publicação: Aplicabilidade dos enxertos impressos tridimensionalmente na reconstrução óssea: uma revisão de escopo
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Pigossi, Suzane Cristina
Resumo
The use of virtual planning and customized 3D-printed bioresorbable structures has been
proposed as a solution to the challenges associated with obtaining and shaping grafts or implants
for reconstructing complex geometric bone defects in the maxillofacial region. This scoping
review provides an overview of the current advancements in virtual planning and custom-made
3D-printed bioresorbable scaffolds, along with their clinical outcomes in maxillofacial
reconstructive surgeries. Electronic searches were conducted across five databases for
publications up to January 2024. Included in the review were reports evaluating patients who
underwent maxillofacial bone defect reconstruction using virtual planning and custom-made
3D-printed bioresorbable scaffolds. Data on postoperative complications, new bone formation,
scaffold resorption, dental implant success/survival, and patient satisfaction were collected. Ten
studies (5 case reports, 4 case series, 1 prospective clinical study) were included. These studies
assessed the effectiveness of 3D-printed scaffolds in reconstructing maxillofacial defects, bone
augmentation for dental implant placement, and regeneration of periosseous defects. Most of
the 3D-printed scaffolds were found to be biocompatible and did not cause local or systemic
adverse events. However, some postoperative complications were reported, including graft
exposure, wound dehiscence, and local infection. Overall, the 3D-printed scaffolds
demonstrated favorable dimensional compatibility with deformities, provided durable support,
promoted bone formation, achieved adequate bone union with host bone tissues, and supported
dental implant placement without the need for additional guided bone regeneration. In
conclusion, custom-made 3D-printed bioresorbable scaffolds, guided by virtual planning,
present a promising option for maxillofacial reconstruction due to their accuracy,
osteoconductivity, and biocompatible properties.
Abstract
The use of virtual planning and customized 3D-printed bioresorbable structures has been
proposed as a solution to the challenges associated with obtaining and shaping grafts or implants
for reconstructing complex geometric bone defects in the maxillofacial region. This scoping
review provides an overview of the current advancements in virtual planning and custom-made
3D-printed bioresorbable scaffolds, along with their clinical outcomes in maxillofacial
reconstructive surgeries. Electronic searches were conducted across five databases for
publications up to January 2024. Included in the review were reports evaluating patients who
underwent maxillofacial bone defect reconstruction using virtual planning and custom-made
3D-printed bioresorbable scaffolds. Data on postoperative complications, new bone formation,
scaffold resorption, dental implant success/survival, and patient satisfaction were collected. Ten
studies (5 case reports, 4 case series, 1 prospective clinical study) were included. These studies
assessed the effectiveness of 3D-printed scaffolds in reconstructing maxillofacial defects, bone
augmentation for dental implant placement, and regeneration of periosseous defects. Most of
the 3D-printed scaffolds were found to be biocompatible and did not cause local or systemic
adverse events. However, some postoperative complications were reported, including graft
exposure, wound dehiscence, and local infection. Overall, the 3D-printed scaffolds
demonstrated favorable dimensional compatibility with deformities, provided durable support,
promoted bone formation, achieved adequate bone union with host bone tissues, and supported
dental implant placement without the need for additional guided bone regeneration. In
conclusion, custom-made 3D-printed bioresorbable scaffolds, guided by virtual planning,
present a promising option for maxillofacial reconstruction due to their accuracy,
osteoconductivity, and biocompatible properties.
Palavras-chave
Impressão tridimensional, Enxerto ósseo, Regeneração óssea, Materiais biocompatíveis, Three-Dimensional Printing, Bone graft, Bone regeneration, Biocompatible materials
Citação
CHIMIRRI, Marcella Cunha. Aplicabilidade dos enxertos impressos tridimensionalmente na reconstrução óssea: uma revisão de escopo. 2024. 42 f. Trabalho de Conclusão de Curso (Graduação em Odontologia) – Universidade Federal de Uberlândia, Uberlândia, 2024.
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