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Efeitos da radiação ionizante na microarquitetura óssea cortical: alterações específicas relacionadas ao longo do tempo

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dc.contributor.advisor1Soares, Priscilla Barbosa Ferreira
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/5032809676969673pt_BR
dc.contributor.referee1Latteshttp://lattes.cnpq.br/5032809676969673pt_BR
dc.contributor.referee2Soares, Carlos José
dc.contributor.referee2Latteshttp://lattes.cnpq.br/3485765805045929pt_BR
dc.contributor.referee3Carvalho, Luciana Arantes Porto
dc.contributor.referee3Latteshttp://lattes.cnpq.br/7743813403256595pt_BR
dc.contributor.referee4Iriê, Milena Suemi
dc.contributor.referee4Latteshttp://lattes.cnpq.br/8678052638631881pt_BR
dc.creatorBorges, Juliana Simeão
dc.creatorRabelo, Gustavo Davi
dc.creatorIriê, Milena Suemi
dc.creatorSpin-Neto, Rubens
dc.creatorPaz, João Lucas Carvalho
dc.creator.Latteshttp://lattes.cnpq.br/1564801167380840pt_BR
dc.date.accessioned2018-06-28T14:57:42Z
dc.date.available2018-06-28T14:57:42Z
dc.date.issued2018-05-22
dc.descriptionPossui versão em CDpt_BR
dc.description.degreenameTrabalho de Conclusão de Curso (Graduação)pt_BR
dc.description.embargo2020-05-21
dc.description.resumoThis study aimed to evaluate the cortical bone microarchitecture in rabbit tibias at intervals 7, 14 and 21 days after ionizing irradiation. Twelve adult male New Zealand rabbits were treated with a single radiation dose of 30Gy. The animals were randomly divided into 4 groups: Control (no radiation), Ir7, Ir14 and Ir21 days. Computadorized microtomography was used to analyze the microarchitecture of the cortical bone. The following parameters were used: cortical thickness (CtTh), bone volume (BV), total porosity (Ct.Po), intracortical porosity (CtPo (cl)), fractal dimension (FD) and degree of anisotropy (Ct.DA). One-way analysis of variance (ANOVA) was performed for all data followed by Tukey and Dunnet tests. The cortical thickness was different (p <0.01) between the control and irradiated groups, with thicker cortex to Ir 7 days. There was no difference between groups for total porosity, however, intracortical porosity revealed significance difference (p <0.001) between the irradiated groups and the control group, with a lower value for Ir7 days. The number of bone channels, fractal dimension and degree of anisotropy did not show significant difference between groups. The bone volume was lower in the Ir14 group in relation to control. In this way, the microarchitecture of the cortical bone can be affected by radiotherapy and the effects appear to be time-dependent. Cortical parameters found in the group Ir21 days were similar to the control group, suggesting that the cortical bone return to the regular conformation after 21 days.pt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo a Pesquisa do Estado de Minas Geraispt_BR
dc.identifier.citationBorges JS, Rabelo GD, Iriê MS, Spin-Neto R, Paz JLC, Soares PBF. Effects of ionizing radiation on cortical bone microarchitecture: specific related alterations over time. 2018. 24 f. Trabalho de Conclusão de Curso (Graduação em Odontologia)- Universidade Federal de Uberlândia, Uberlândia, 2018.pt_BR
dc.identifier.urihttps://repositorio.ufu.br/handle/123456789/21663
dc.languageengpt_BR
dc.publisherUniversidade Federal de Uberlândiapt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.courseOdontologiapt_BR
dc.rightsAcesso Abertopt_BR
dc.sizeorduration24pt_BR
dc.subjectRadiotherapypt_BR
dc.subjectCortical bonept_BR
dc.subjectMicroarchitecturept_BR
dc.subjectComputadorizedpt_BR
dc.subjectMicrotomographypt_BR
dc.subject.cnpqCNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA::RADIOLOGIA ODONTOLOGICApt_BR
dc.titleEfeitos da radiação ionizante na microarquitetura óssea cortical: alterações específicas relacionadas ao longo do tempopt_BR
dc.title.alternativeEffects of ionizing radiation on cortical bone microarchitecture: specific related alterations over timept_BR
dc.typeTrabalho de Conclusão de Cursopt_BR
dspace.entity.typePublication

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TCC - Odontologia