https://repositorio.ufu.br/handle/123456789/21773 2026-04-10T22:31:18Z https://repositorio.ufu.br/handle/123456789/46842 Title: O novo ensino médio e a base nacional comum curricular no ensino de química: revisão bibliográfica dos anais do ENEQ (2023 e 2024) Abstract: Esta monografía tiene como objetivo identificar los trabajos publicados en las actas de las dos últimas ediciones del Encuentro Nacional de Enseñanza de la Química (ENEQ) (2023 y 2024), en lo que respecta a la temática del Nuevo Bachillerato (NEM) y de la Base Nacional Común Curricular (BNCC). Dicho evento constituye el encuentro científico más importante en el área de la Enseñanza de la Química en Brasil y, por lo tanto, se destaca por promover reflexiones pertinentes a la comunidad académica y escolar involucrada en la Educación Química. Para ello, en un primer momento se desarrolla una revisión documental de los archivos del NEM, de la BNCC y del Currículo de Referencia de Minas Gerais (CRMG). Posteriormente, se realiza una revisión bibliográfica que toma como material dieciocho trabajos que constituyen el corpus de la investigación, los cuales fueron publicados en las actas de la XXI y XXII ediciones del ENEQ (2023 y 2024). Los resultados de la investigación señalan que ha habido un aumento de trabajos publicados en las actas de los ENEQ en relación con la temática del NEM y de la BNCC. Además, que las principales temáticas abordadas son: BNCC y sus desarrollos; Currículos estatales e itinerarios formativos; Enfoques didácticos alternativos y ludicidad; Condiciones de trabajo docente; y Formación docente y prácticas pedagógicas. Por lo tanto, este estudio muestra hasta qué punto el NEM y la BNCC se han convertido en un campo de interés e investigación en lo que respecta a las producciones y estudios en la Enseñanza de la Química. Notes: 100 2025-09-11T00:00:00Z https://repositorio.ufu.br/handle/123456789/46096 Title: Uma análise das percepções dos estudantes sobre a escola de educação básica: resultados de uma pesquisa desenvolvida no âmbito do Programa Residência Pedagógica 2025-04-30T00:00:00Z https://repositorio.ufu.br/handle/123456789/45947 Title: Estudo de degradação forçada do cloridrato de ranitidina para avaliação da geração de nitrosaminas Abstract: The administration of medications was a turning point in history, allowing previously deadly diseases to become treatable. The pharmaceutical industry is one of the largest sectors of the global economy. According to ANVISA, the sale of medications generates more than 130 billion reais per year in Brazil. This scenario implies large-scale production for consumption, making it essential to rigorously verify the quality and safety of medications to ensure that they do not pose health risks. Recently, studies indicated the formation of N-nitrosodimethylamine (NDMA), a potentially toxic compound, in medicines with the active pharmaceutical ingredient (API) ranitidine hydrochloride. The ban on marketing was worldwide, and the episode revealed the need for greater control over production. Considering the possibility of formation of these compounds with carcinogenic potential, in the present study, a forced degradation study of the drug ranitidine, used to treat gastric ulcers, was carried out to evaluate the degradation products generated and the potential generation of NDMA. The drug was subjected to stress conditions: thermolysis, acid hydrolysis, basic hydrolysis, oxidation, and photolysis. The method used was based on the ANVISA degradation guide, Resolution No. 4/2015, to evaluate the generation of nitrosamines, especially NDMA. Chromatographic analysis was performed by high-performance liquid chromatography (HPLC), using a C18 column and mobile phase composed of ACN:H2O with gradient elution and detection performed by a diode array detector at 228 nm. Forced degradation tests led to the formation of seven ranitidine degradation products (DPs). Under more extreme conditions (prolonged time and/or higher concentrations of degrading agents), complete degradation of the drug was observed. Of these DPs formed, the formation of the toxic compound NDMA stood out, observed specifically in hydrolytic degradations under heating. Confirmation of the identity of NDMA was performed by comparison with analysis of the analytical standard of NMDA, under the same analysis conditions. Ranitidine DPs were identified through chromatographic profile analysis and comparison with the ranitidine chromatograms and byproducts published in the literature. Thus, the forced degradation of ranitidine proved efficient and valuable in evaluating the potential generation of toxic products from the degradation of ranitidine hydrochloride. 2025-05-30T00:00:00Z https://repositorio.ufu.br/handle/123456789/45750 Title: Desenvolvimento de sorvente monolítico polimérico impresso molecularmente para extração em ponteira descartável de BDE-209 Abstract: Flame retardants are chemical substances used to reduce the flammability of materials and are widely applied in sectors such as construction, automotive, electronics, and textiles to enhance fire safety. However, traditional halogenated flame retardants pose environmental and health risks due to the release of toxic compounds. Disposable pipette tip extraction (DPX) has emerged as a promising sample preparation technique, offering speed, reduced solvent consumption, and high extraction efficiency. Nevertheless, commercially available particulate sorbents have limitations such as low selectivity and reproducibility, and require filters, increasing device costs. Monolithic sorbents, prepared directly inside the pipette tip, eliminate this need and offer advantages including good permeability, mechanical stability, and functionalization via molecular imprinting (MIP), which enhances sorbent selectivity. This study aimed to develop a hydrophobic, hierarchically porous monolithic polymer sorbent for pipette tip application, based on the polymerization of trimethylolpropane triacrylate (TMPTA) and ethylene glycol dimethacrylate (EDMA), molecularly imprinted with decabromodiphenyl ether (BDE-209). The monolith preparation was optimized using a central composite design with two variables: polymerization time and temperature. The materials were characterized by water permeability (~5 mL min⁻¹), scanning electron microscopy, infrared spectroscopy, and thermogravimetric analysis, confirming a homogeneous, highly porous, and thermally stable structure up to ~325 °C. The poly(TMPTA-co-EDMA) monoliths exhibited a specific surface area of ~250 m² g⁻¹. Extraction performance evaluation showed that the MIP monoliths achieved approximately 1.7 times greater BDE-209 extraction compared to NIP. Thus, DPX with molecularly imprinted polymeric monolithic sorbents for BDE-209 proved to be a viable and selective approach for efficient flame retardant extraction. 2025-05-09T00:00:00Z