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Manifestações orais de doenças imunomediadas: evidências clínicas e epidemiológicas de um serviço de referência regional

2026-09-22T06:19:41Z

Title: Manifestações orais de doenças imunomediadas: evidências clínicas e epidemiológicas de um serviço de referência regional Abstract: This study addresses immune-mediated diseases with oral manifestations, a heterogeneous group of conditions that significantly impact patients' quality of life and pose diagnostic challenges due to overlapping clinical features among different diseases. The research was conducted at a regional referral center, the Dental Hospital of the Federal University of Uberlândia, and comprised two complementary investigations. The first consisted of a retrospective observational analysis of the clinical, demographic, and therapeutic characteristics of patients diagnosed with oral lichen planus. The second explored the coexistence of psoriasis and oral pemphigus vulgaris, discussing potential underlying immunopathological mechanisms. Together, these studies highlight the importance of clinicopathological correlation, multidisciplinary management, and longitudinal follow-up in the care of patients with oral immune-mediated diseases, contributing to the improvement of diagnostic and therapeutic strategies within the Brazilian Unified Health System.

Terapia a laser de baixa intensidade e gel à base de fluoreto, sílica e cálcio para o controle da hipersensibilidade dentinária: estudo clínico randomizado controlado.

2026-09-19T06:24:21Z

Title: Terapia a laser de baixa intensidade e gel à base de fluoreto, sílica e cálcio para o controle da hipersensibilidade dentinária: estudo clínico randomizado controlado. Abstract: The present study aimed to evaluate the isolated and combined effects of a fluoride/silica/calcium (FSC) gel and low-level laser therapy (LLLT) in the management of dentin hypersensitivity (DH). Forty-five patients with DH presenting at least one tooth with exposed cervical dentin on the buccal surface were included. DH was confirmed by a positive response of ≥40 mm on the Visual Analog Scale (VAS) following air and water stimulation. Participants were randomly allocated to three groups: FSC (fluoride/silica/calcium gel), LLLT (low-level laser therapy), and FSC/LLLT (combined therapy). The FSC and FSC/LLLT groups received three in-office applications of the FSC gel at 72-hour intervals, combined with home use of the gel for two months, followed by replacement with a fluoride/silica gel (without the calcium booster) for three months. The LLLT and FSC/LLLT groups received laser applications during the first three treatment sessions and at follow-up visits after 7 days, 15 days, 1 month, and 3 months. Pain was assessed following evaporative and tactile stimuli using the VAS and the Schiff Cold Air Sensitivity Scale at baseline, immediately after each treatment session, and at the 7-day, 15-day, 1-month, and 3-month follow-up visits. Oral health-related quality of life was assessed using the Dentine Hypersensitivity Experience Questionnaire (DHEQ-15) at baseline and throughout the follow-up period. All groups exhibited an immediate reduction in pain elicited by evaporative stimulation after the first intervention, with no significant differences among treatments. A similar pattern was observed after the second and third treatment sessions. Compared with baseline, all groups showed a gradual reduction in pain over time. For tactile sensitivity and Schiff scale assessments, only the LLLT group demonstrated significant reductions immediately after the first three treatment sessions, whereas all groups exhibited significant improvements over time. Oral health-related quality of life also improved in all groups. It can be concluded that both the FSC gel and LLLT were effective in reducing pain and improving the quality of life of patients with DH. However, the combination of these therapies did not provide additional benefits compared with either treatment alone, suggesting similar clinical efficacy among the treatment approaches.

Efeito da fotobiomodulação infravermelha associada à proteína da matriz do esmalte na formação óssea com osso bovino desproteinizado em ratos

2026-08-29T06:25:11Z

Title: Efeito da fotobiomodulação infravermelha associada à proteína da matriz do esmalte na formação óssea com osso bovino desproteinizado em ratos Abstract: Objective: This study evaluated whether the combination of infrared photobiomodulation therapy (IR-PBMT) and enamel matrix derivative (EMD) enhances the repair of areas grafted with deproteinized bovine bone (DBB). Material and methods: Forty-eight rats were used. Surgery was performed bilaterally in the mandible, with both sides allocated to the same experimental group. The animals were evaluated at two experimental periods (30 and 90 days; n = 6). A dome shaped Teflon was placed in the mandibular ramus of each animal, bilaterally, and filled with DBB. The groups were divided according to the type of treatment applied to the grafted area: DBB: no adjunct treatment; EMD: DBB associated with EMD; IR-PBMT: DBB subjected to IR-PBMT; IRPBMT/EMD: DBB associated with EMD + IR-PBMT. The following analyses were performed: (1) micro-computed tomography, to evaluate the volume and microstructure of the grafted area, and (2) histomorphometry, to assess the composition of the repaired tissue. Results: The DBB and IR-PBMT/EMD groups showed greater mineralized tissue volume and smaller trabecular spacing compared to the other groups (p<0.05). The DBB group showed a smaller amount of bone than all other groups at 30 days (p<0.05). The IR-PBMT/EMD group showed a greater amount of bone than the other groups at 90 days (p<0.05). Conclusion: The combined treatment with IRPBMT and EMD enhances repair in areas grafted with DBB.

Desenvolvimento de uma tecnologia educacional digital em saúde bucal para adultos e idosos

2026-08-26T06:18:50Z

Title: Desenvolvimento de uma tecnologia educacional digital em saúde bucal para adultos e idosos Abstract: The incorporation of digital educational technologies in the health field has expanded the possibilities for health promotion, health education, and strengthening self-care. In this context, oral health education aimed at adults and older adults requires innovative, accessible strategies that are aligned with the needs of this population. This study aimed to develop an interactive website for oral health education directed at adult and older adult users of public health services. The dissertation was structured into three chapters. The first chapter consisted of a scoping review designed to map the scientific evidence on the applicability of digital technologies for oral health education among adults and older adults. The research question was developed based on the PCC framework (Population, Concept, and Context), in which the Population (P) referred to adults and older adults, the Concept (C) to educational technologies in health, and the Context (C) to oral health education. Thus, the following question was proposed: “What is the applicability of educational health technologies available for oral health education among adults and older adults?” The search and selection of studies took place between October 2025 and May 2026. Ten studies were included. The most frequently addressed topic in the articles was oral hygiene, and the most common strategy was the use of digital educational videos. The main outcomes showed increased knowledge, improved self-efficacy and self care, positive behavioral changes, and reductions in clinical indicators, such as dental plaque and tongue coating. The second chapter presented the development of the @ViverSorrindo website for oral health education aimed at adults and older adults. The platform integrated different educational resources, including videos, illustrative images, texts with audio narration, quizzes, simulation scenarios, and a myths-and-truths game, presented in an accessible format adapted to the needs of adults and older adults. The third chapter corresponded to the development of an informational folder for the use of the @ViverSorrindo website. The material was designed to facilitate users’ access to and navigation through the platform, expanding its potential use in health services and educational activities. Thus, the studies included in the scoping review showed that oral hygiene was the most prevalent topic, and digital educational videos were the most frequently addressed strategy. Based on these findings, the @ViverSorrindo website represents a practical, free, and accessible digital educational technology with the potential to support health promotion and oral health education actions aimed at the adult and older adult population. This tool may favor access to information and communication between users and health professionals, constituting a possible complementary strategy for comprehensive care and healthy aging.