https://repositorio.ufu.br/handle/123456789/5158 2026-07-31T17:51:40Z 2026-07-31T17:51:40Z https://repositorio.ufu.br/handle/123456789/49213 2026-07-31T12:27:56Z 2026-07-15T00:00:00Z

Title: Impacto da radioterapia de cabeça e pescoço nos tecidos dentários: alterações estruturais e efeito de dentifrícios fluoretados Abstract: Radiotherapy is one of the main therapeutic modalities used in the treatment of head and neck cancer. However, it may lead to complex oral complications. Radiation-related caries (RRC) is characterized by a more rapid and aggressive progression than conventional dental caries, typically initiating with enamel cracking and delamination, followed by dentin exposure to the oral environment. The direct effects of ionizing radiation on dental tissues include changes in microhardness, disruption of the collagen network, and obliteration of dentinal tubules, making the management of this condition particularly challenging and highlighting the importance of preventive strategies. Although the efficacy of fluoride is well established, evidence regarding the effects of different fluoride concentrations on irradiated dental substrates remains limited. The aim of this thesis was to evaluate the structural alterations induced by radiotherapy in dental tissues and to investigate the effects of toothpastes containing different fluoride concentrations on irradiated tissues through complementary studies, encompassing structural and crystallographic changes as well as the response of dental tissues to fluoride-based preventive strategies. To achieve this, three in vitro laboratory studies were conducted, presented as Chapters 1, 2, and 3. Chapter 1 aimed to correlate the mechanical and solubility properties of enamel with radiation-induced crystallographic changes, considering the proximity to the dentino-enamel junction (DEJ). The methodologies included two-dimensional synchrotron radiation X-ray microdiffraction (SR-µXRD), Vickers microhardness, fracture toughness, and citric and lactic acid solubility tests. The irradiated enamel exhibited lower microhardness values and greater acid solubility than the non-irradiated enamel. Furthermore, SR-µXRD revealed changes in the crystallographic parameters and texture of irradiated hydroxyapatite. Chapter 2 investigated the effects of radiation on the surface properties of demineralized human dentin following pH cycling and toothpaste treatment. Knoop microhardness, Atomic Force Microscopy (AFM), and Scanning Electron Microscopy (SEM) were employed. Under the in vitro conditions of this study, irradiated and non-irradiated dentin showed similar behavior regarding microhardness and surface roughness after being subjected to the same pH-cycling protocol and treatment with fluoride toothpastes. Chapter 3 evaluated the effects of toothpastes containing different fluoride concentrations on the mechanical and surface properties of irradiated and non-irradiated dentin after pH cycling. The same methodologies described in Chapter 2 were used. The results demonstrated that different fluoride concentrations produced distinct responses in irradiated dentin. The toothpaste containing 5,000 ppm fluoride resulted in higher microhardness values and lower surface roughness than the fluoride-free toothpaste and the 1,450 ppm fluoride toothpaste. In conclusion, head and neck radiotherapy promotes significant structural changes in dental tissues, as evidenced by crystallographic alterations in enamel hydroxyapatite. Furthermore, fluoride toothpastes demonstrated the potential to mitigate the deleterious effects of ionizing radiation on dentin.

2026-07-15T00:00:00Z https://repositorio.ufu.br/handle/123456789/49187 2026-07-31T06:23:52Z 2026-06-26T00:00:00Z

Title: Guia clínico para restaurações de cavidade classe II com resina composta: protocolo prático e estratégias clínicas Abstract: Introduction: Class II restorations in posterior teeth represent a recurring challenge in clinical dental practice, especially regarding the achievement of adequate proximal contacts, marginal adaptation, and anatomical reconstruction. In this context, the correct execution of operative procedures and the appropriate selection of materials and matrix systems are determining factors for clinical success. Objective: To develop a technical-demonstrative clinical guide for Class II composite resin restorations, addressing the operative procedures, materials used, and clinical strategies related to achieving predictable restorative outcomes. Methodology: This is a descriptive study with a technical-demonstrative approach associated with a narrative literature review. The review was conducted using electronic databases, focusing on evidence related to Class II restorations and matrix systems. The practical stage was performed on a dental model containing a Class II cavity in tooth 36, using circumferential and sectional matrix systems. The clinical procedures were carried out in a standardized manner and documented through sequential photographic records. Results: It was possible to describe a detailed restorative protocol, highlighting the clinical procedures, materials used, and relevant operative strategies, including the use of matrix systems to obtain adequate proximal contacts. Conclusion: The proper execution of operative procedures, associated with the correct selection of materials and matrix systems, contributes to greater predictability and quality of Class II restorations, making the proposed guide a useful educational resource for clinical practice.

2026-06-26T00:00:00Z https://repositorio.ufu.br/handle/123456789/49171 2026-07-31T06:20:34Z 2024-04-26T00:00:00Z

Title: Percepções de pais e estudantes de odontologia sobre a estabilização protetora: uma revisão de escopo Abstract: Protective stabilization, also referred to as physical restraint or restraint, involves limiting the patient's movements during pediatric dental treatment. This procedure is carried out with the aim of reducing the risk of injury and damage, ensuring a safe and secure approach to treatment. The objective of this scoping review was to systematically map the research carried out on the perception of parents and dentistry students regarding the protective stabilization technique, as well as identify existing knowledge gaps. The following research question was formulated: what is known in the literature about the perception of parents and dental students regarding the protective stabilization technique? Therefore, the scoping review included qualitative studies carried out with the participation of and parents/caregivers of children with or without disabilities dentistry students, published between 2014 and 2024 in the SCIELO, Virtual Health Library (VHL) and MEDLINE®/PubMED®, in Portuguese and English. 379 articles were identified, with three studies selected to compose the present review. The studies found were synthesized and categorized according to the main themes: challenges and difficulties of parents and/or caregivers of children in relation to the use of the protective stabilization technique and dentistry students' perception of the protective stabilization technique. Analysis of the perceptions of parents and dentistry students regarding protective stabilization in pediatric dentistry reveals a variety of feelings and attitudes towards this technique. While some recognize its relevance to treatment success, others express concerns about the possible emotional impact on children.

2024-04-26T00:00:00Z https://repositorio.ufu.br/handle/123456789/49163 2026-07-30T06:25:25Z 2026-03-02T00:00:00Z

Title: Guia prático de dessensibilização: manejo da hipersensibilidade dentinária Abstract: Dentin hypersensitivity (DH) is characterized by a sharp, short-lasting pain arising from exposed dentin in response to thermal, evaporative, tactile, osmotic, or chemical stimuli, in the absence of any other identifiable dental pathology. With an estimated global prevalence of approximately 11.5%, it represents a frequent clinical challenge due to its multifactorial etiology, the lack of a standardized therapeutic protocol, and the wide range of available desensitizing agents. The present study aimed to develop a practical guide to assist dentists and undergraduate students in the diagnosis and management of dentin hypersensitivity. This study consists of a clinical case report associated with the development of a technical-educational product, conducted at the Integrated Clinic of the School of Dentistry of the Federal University of Uberlândia, with approval from the Research Ethics Committee. A detailed anamnesis was performed, etiological factors were identified, neural and obliterating desensitizing agents were sequentially applied, and pain levels were reassessed using the Visual Analog Scale (VAS). The literature indicates that desensitizing agents may act either by modulating neural transmission or by occluding dentinal tubules, with no consensus regarding the superiority of a single approach. Considering that the hydrodynamic theory proposed by Brännström—based on intratubular fluid movement as the mechanism responsible for pain—is the most widely accepted pathophysiological model to explain dentin hypersensitivity, obliterating agents demonstrate consistent biological rationale, as they directly reduce or block this fluid displacement. Clinical evidence suggests that both neural and obliterating agents can significantly reduce pain, and their combined use represents a plausible and rational strategy for the clinical management of DH. It can be concluded that the development of an evidence-based practical guide contributes to the systematization of clinical conduct, promoting greater safety in the management of DH and expanding its applicability, including in public healthcare settings.

2026-03-02T00:00:00Z