https://repositorio.ufu.br/handle/123456789/21759 2026-08-06T22:03:29Z 2026-08-06T22:03:29Z https://repositorio.ufu.br/handle/123456789/49054 2026-07-25T06:26:58Z 2026-03-12T00:00:00Z

Title: Análise comparativa da composição bioquímica de vinhos produzidos com as uvas Sauvignon Blanc, Cabernet Blanc, Chardonnay & Sémillon e Moscato

2026-03-12T00:00:00Z https://repositorio.ufu.br/handle/123456789/49031 2026-07-24T06:19:34Z 2026-03-13T00:00:00Z

Title: Determinação voltamétrica de ácido salicílico em amostras de leite com um eletrodo de fio de cobre Abstract: Salicylic acid (SA) is widely used in the dermatological and pharmaceutical industries due to its antiseptic, anti-inflammatory, and exfoliating properties; however, its use as a food additive is not permitted. Despite this prohibition, cases of milk adulteration with SA are frequently reported in several countries. Besides compromising the quality of milk and dairy products, this adulteration represents a serious health risk to consumers, demonstrating the relevance of efficient analytical methods for the quantification of SA in complex matrices such as milk. This work presents an environmentally friendly voltammetric method for the determination of SA in milk, using a working electrode made of commercial copper wires, subsequently subjected to a chemical modification in an alkaline medium to form a CuO-rich layer that protects against electrode fooling and improves the electrochemical response of SA. The technique employed was Differential pulse voltammetry, which, after parameter optimization, yielded a linear range of 10 to 500 µmol L⁻¹ and a detection limit of 3.0 µmol L⁻¹. Another highlight is the sample treatment using only ZnSO₄ and NaOH, the former precipitates milk proteins, while the latter ionizes the SA, facilitating its extraction and subsequent detection. This procedure reduces reagent and sample consumption, eliminates organic solvents, and allows for rapid pre-treatment of multiple samples simultaneously. In the spike-and-recovery study for fortified samples, the recovery percentages of AS ranged from 91 to 107%, with RSD values from 2.1 to 5.3%, results consistent with the AOAC guidelines for evaluating the performance of analytical methods. Therefore, this work offers a low-cost procedure, more sustainable than the established method for determining AS in food, and with satisfactory analytical performance, representing a promising strategy for the quantification of AS in milk samples.

2026-03-13T00:00:00Z https://repositorio.ufu.br/handle/123456789/48998 2026-07-24T06:19:21Z 2026-03-16T00:00:00Z

Title: Menopausa e Encéfalo: O que revela a Literatura Científica Abstract: The menopausal transition (MT) is a phase experienced by women during midlife, characterized by profound hormonal changes that may affect multiple aspects of physical and mental health. During this period, the decline in estrogen and progesterone production leads to physiological alterations that can impact several body systems, significantly influencing brain function in women undergoing this transition. The aim of this review was to evaluate the morphological and bioenergetic brain changes associated with menopause in the context of female aging, as well as to discuss the options and effects of hormone therapy for managing the alterations experienced during this period. This was conducted through the selection of scientific articles derived from research studies carried out exclusively in women (human subjects), published between 2014 and 2024 in the PubMed database. The findings indicate that the female brain undergoes substantial changes during the MT, including marked reductions in gray matter volume in more rostral regions, such as the frontal and temporal cortices, as well as in limbic areas including the hippocampus and amygdala—regions that play key roles in the modulation of cognitive functions, memory, and emotions. In addition, increases in white matter hyperintensity volume were observed, potentially rendering the brain more susceptible to dementia, alongside metabolic and bioenergetic transitions. Hormone replacement therapy (HRT) appears to exert a neuroprotective effect; however, this effect is dependent on factors such as the timing of treatment initiation, the specific formulation used, and dosage. The lack of longitudinal studies, as well as inconsistencies in HRT protocols, represent notable limitations in the literature reviewed and highlight the need for further research aimed at achieving a more comprehensive understanding of female brain aging.

2026-03-16T00:00:00Z https://repositorio.ufu.br/handle/123456789/48997 2026-07-24T06:19:19Z 2026-03-20T00:00:00Z

Title: Análise comparativa de métodos de extração e solventes utilizados para a avaliação antioxidante de frutos de pimenta-rosa (Schinus terebinthifolia Raddi) Abstract: Pink pepper (Schinus terebinthifolia Raddi) is a Brazilian native species and is widely used in gastronomy and in folk medicine, recognized for its antioxidant potential, which is associated with secondary metabolites presence, above all phenolic compounds and flavonoids. This study aimed to comparatively analyze the extraction methods and solvents employed in the evaluation of the antioxidant activity of pink pepper fruits, as well as their influence on the chemical profile of the obtained extracts. A systematic literature review was conducted between October 2025 and February 2026, using Google Schoolar, PubMed, Scielo and Science Direct databases. Scientific articles were selected according to previously defined inclusion and exclusion criteria, totaling seven analyzed studies. The results revealed high variability in the extraction methods, including maceration, Soxhlet, ultrasound-assisted extraction, and pressurized liquid extraction, as well as the use of solvents with different polarities and in varied proportions. Solvents with higher polarity were associated with greater efficiency in the extraction of antioxidant compounds, whereas solvents with intermediate polarity showed a balance between extraction yield and antioxidant activity. It was also observed that energy-assisted extraction methods tend to reduce the time of extraction; however, they may promote sensitive compounds degradation depending on the conditions employed. It was concluded that the antioxidant potential of Schinus terebinthifolia fruits can be directly influenced by the extraction method, the solvent and the experimental conditions used, and that the lack of methodological standardization limits direct comparisons among studies, reinforcing the need for controlled comparative research.

2026-03-20T00:00:00Z